发明名称 |
DIFFERENT LEVELS IN BLOOD CELL SAMPLES OF EMT-MARKERS FOR THE DIAGNOSIS OF CANCER, IN PARTICULAR OF COLORECTAL (CRC) AND PANCREATIC (PC) CANCER |
摘要 |
The present invention concerns a method for determining if a subject is affected by a colorectal or pancreatic cancer or for determining the stage, the remission or the progression of a colorectal cancer by measuring the presence of a panel of mRNAs encoding for transcription factors involved in epithelial to mesenchymal transition in a biological sample, wherein mRNA levels of TWIST1, SLUG and ZEB2 genes, are indicative of diagnosis or of partial or full remission of colorectal cancer, and/or colorectal cancer stage variation and/or treatment responsiveness. The invention concerns also kits to work the method. |
申请公布号 |
EP3083988(A2) |
申请公布日期 |
2016.10.26 |
申请号 |
EP20140818946 |
申请日期 |
2014.12.16 |
申请人 |
HUMANITAS MIRASOLE S.P.A. |
发明人 |
LAGHI, LUIGI;CELESTI, GIUSEPPE |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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