发明名称 DIFFERENT LEVELS IN BLOOD CELL SAMPLES OF EMT-MARKERS FOR THE DIAGNOSIS OF CANCER, IN PARTICULAR OF COLORECTAL (CRC) AND PANCREATIC (PC) CANCER
摘要 The present invention concerns a method for determining if a subject is affected by a colorectal or pancreatic cancer or for determining the stage, the remission or the progression of a colorectal cancer by measuring the presence of a panel of mRNAs encoding for transcription factors involved in epithelial to mesenchymal transition in a biological sample, wherein mRNA levels of TWIST1, SLUG and ZEB2 genes, are indicative of diagnosis or of partial or full remission of colorectal cancer, and/or colorectal cancer stage variation and/or treatment responsiveness. The invention concerns also kits to work the method.
申请公布号 EP3083988(A2) 申请公布日期 2016.10.26
申请号 EP20140818946 申请日期 2014.12.16
申请人 HUMANITAS MIRASOLE S.P.A. 发明人 LAGHI, LUIGI;CELESTI, GIUSEPPE
分类号 C12Q1/68 主分类号 C12Q1/68
代理机构 代理人
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