发明名称 GENE SIGNATURE BIOMARKERS OF TUMOR RESPONSE TO PD-1 ANTAGONISTS
摘要 The present disclosure describes gene signature biomarkers that are useful for identifying cancer patients who are most likely to benefit from treatment with a PD-1 antagonist. The disclosure also provides methods and kits for testing tumor samples for the biomarkers, as well as methods for treating subjects with a PD-1 antagonist based on the test results.
申请公布号 EP3084001(A2) 申请公布日期 2016.10.26
申请号 EP20140871078 申请日期 2014.12.15
申请人 MERCK SHARP & DOHME CORP. 发明人 AYERS, MARK;LOBODA, ANDREY;LUNCEFORD, JARED;MCCLANAHAN, TERRILL, K.;MURPHY, ERIN;NEBOZHYN, MICHAEL;PIERCE, ROBERT, H.
分类号 C12Q1/68 主分类号 C12Q1/68
代理机构 代理人
主权项
地址