发明名称 |
STENTS WITH DRUG ELUTING COATINGS |
摘要 |
Provided is a coated medical device (e.g., a stent) comprising one or more surfaces having dispersed thereon a plurality of microparticles comprising an active pharmaceutical ingredient (API) and a polymer. Specifically, the microparticles are disposed on a device surface in a microparticulate phase coating, i.e., as discrete microparticles in the absence of a continuous phase coating. The medical device effectively adheres one or more APIs to its surface, and allows controlled release of the APIs from the device surface to a desired treatment area by using a minimal amount of polymer. The medical device is suitable for insertion or implantation into a subject, preferably a human. Also provided are methods for preparing and using the coated medical device. |
申请公布号 |
EP2086600(B1) |
申请公布日期 |
2016.10.26 |
申请号 |
EP20070870838 |
申请日期 |
2007.11.01 |
申请人 |
BOSTON SCIENTIFIC LIMITED |
发明人 |
MALONE, ANTHONY;O'CONNOR, TIM;MCMORROW, DAVE;FLANAGAN, AIDEN |
分类号 |
A61L31/10;A61L27/34;A61L27/54;A61L29/08;A61L29/16;A61L31/14;A61L31/16 |
主分类号 |
A61L31/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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