发明名称 |
IMIDAZOPYRIDAZINE DERIVATIVES AS GABAA RECEPTOR MODULATORS |
摘要 |
The present invention relates to imidazopyridazine derivatives. More particularly, it relates to 4-(biphenyl-3-yl)-7H-imidazo[4,5-c]pyridazine derivatives of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are as defined in the description. The imidazopyridazine derivatives of the present invention modulate the activity of the GABAA receptor. They are useful in the treatment of a number of conditions, including pain. |
申请公布号 |
EP2938615(B1) |
申请公布日期 |
2016.10.26 |
申请号 |
EP20130812165 |
申请日期 |
2013.12.04 |
申请人 |
PFIZER LIMITED |
发明人 |
OMOTO, KIYOYUKI;OWEN, ROBERT MCKENZIE;PRYDE, DAVID CAMERON;WATSON, CHRISTINE ANNE LOUISE;TAKEUCHI, MIFUNE |
分类号 |
C07D487/04;A61K31/5025;A61K45/06;A61P29/00 |
主分类号 |
C07D487/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|