| 发明名称 |
3-SPIRO-7-HYDROXAMIC ACID TETRALINS AS HDAC INHIBITORS |
| 摘要 |
The present invention is directed to compounds of Formulae I and II which are inhibitors of histone deacetylases (HDACs) such as HDAC6, and their use in the treatment of diseases such as cell proliferative diseases (e.g., cancer), neurological (e.g., neurodegenerative disease or neurodevelopmental disease), inflammatory or autoimmune disease, infection, metabolic disease, hematologic disease, or cardiovascular disease. |
| 申请公布号 |
WO2016168660(A1) |
申请公布日期 |
2016.10.20 |
| 申请号 |
WO2016US27842 |
申请日期 |
2016.04.15 |
| 申请人 |
FORMA THERAPEUTICS, INC. |
发明人 |
NG, Pui Yee;DAVIS, Heather;BAIR, Kenneth W.;MILLAN, David S.;RUDNITSKAYA, Aleksandra;ZHENG, Xiaozhang;HAN, Bingsong;BARCZAK, Nicholas;LANCIA JR., David |
| 分类号 |
C07D221/20;A61K31/438;C07D209/96;C07D401/04;C07D401/06;C07D403/04;C07D403/06;C07D405/04;C07D405/06;C07D413/06;C07D417/06;C07D471/04;C07D491/107;C07D495/10;C07D519/00 |
主分类号 |
C07D221/20 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
