发明名称 |
BRANCHED HETERO-POLYETHYLENE GLYCOL AND INTERMEDIATE |
摘要 |
A purpose of the present invention is to provide a branched hetero polyethylene glycol compound having two kinds of functional groups capable of reacting with various bio-functional substances and having one of the functional groups plurally. A branched hetero polyethylene glycol according to the present invention is represented by the formula [1]:
wherein X and Y represent each an atomic group containing at least a functional group which reacts with a functional group present in a bio-functional molecule to form a covalent bond and the functional group contained in the atomic group X and the functional group contained in the atomic group Y are different from each other; s is an integer of 2 to 8, which represents the number of polyethylene glycol chains; n is the number of average added moles for the polyethylene glycol chain and 20‰¤n‰¤2000; and E is a branching linker moiety having s-valent bonding valency for the polyethylene glycol chains and having monovalent bonding valency for the functional group Y. |
申请公布号 |
EP2586811(A4) |
申请公布日期 |
2016.10.19 |
申请号 |
EP20110798136 |
申请日期 |
2011.06.21 |
申请人 |
NOF CORPORATION |
发明人 |
YAMAMOTO YUJI;YOSHIOKA HIROKI;MANABE FUMIAKI |
分类号 |
C08G65/32;A61K47/48;C08G65/26;C08G65/325;C08G65/331;C08G65/333;C08G65/334 |
主分类号 |
C08G65/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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