发明名称 |
SOLID FORM OF ABIRATERONE ACETATE |
摘要 |
Combinations of (3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-yl acetate (Abiraterone acetate) with acidic substances such as citric acid, ascorbic acid, methyl-4-hydroxy benzoate, saccharin, vanillic acid, adipic acid, maleic acid, malic acid, tartaric acidare useful as pharmaceutical preparations and show improved properties such as aqueous solubility and dissolution kinetics, especially in the form of cocrystals or their combination with a suitable acid. |
申请公布号 |
EP3080141(A1) |
申请公布日期 |
2016.10.19 |
申请号 |
EP20140809636 |
申请日期 |
2014.12.09 |
申请人 |
BASF SE |
发明人 |
CHIODO, TIZIANA;SALVADOR, BEATE;VOSSEN, MARCUS;HAFNER, ANDREAS;HINTERMANN, TOBIAS;SZELAGIEWICZ, MARTIN;BLATTER, FRITZ;VIERTELHAUS, MARTIN;WEISHAAR, WALTER |
分类号 |
C07J43/00;A61K9/14;A61K31/58;A61P35/00 |
主分类号 |
C07J43/00 |
代理机构 |
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代理人 |
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地址 |
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