发明名称 |
ANTIDIABETIC BICYCLIC COMPOUNDS |
摘要 |
Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia. |
申请公布号 |
EP3076959(A1) |
申请公布日期 |
2016.10.12 |
申请号 |
EP20140868525 |
申请日期 |
2014.12.01 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
BARA, THOMAS;CHOBANIAN, HARRY;GUO, YAN;JOSIEN, HUBERT;MILLER, MICHAEL;PIO, BARBARA;PLUMMER, CHRISTOPHER W.;YANG, CANGMING;XIAO, DONG |
分类号 |
A61K31/075 |
主分类号 |
A61K31/075 |
代理机构 |
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代理人 |
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地址 |
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