发明名称 Antibodies that immunospecifically bind to BLyS
摘要 The present invention relates to antibodies and related molecules that immunospecifically bind to BLyS. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant BLyS expression or inappropriate function of BLyS comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to BLyS. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant BLyS expression or inappropriate BLyS function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to BLyS.
申请公布号 EP2281843(B1) 申请公布日期 2016.10.12
申请号 EP20100185185 申请日期 2001.06.15
申请人 HUMAN GENOME SCIENCES, INC. 发明人 RUBEN, STEVEN M.;BARASH, STEVEN C.;CHOI, GIL H.;VAUGHAN, TRISTAN;HILBERT, DAVID
分类号 C07K16/28;G01N33/53;A61K45/00;A61K47/48;A61K49/00;A61P35/00;A61P37/00;A61P37/04;A61P37/06;C07K14/52;C07K14/705;C07K16/18;C07K16/46;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/08;G01N33/564 主分类号 C07K16/28
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