| 摘要 |
The invention provides a method of detecting or monitoring a malignant plasma cell disease comprising detecting in a sample the ratio between the relative amounts of immunoglobulins having:
(i) a heavy chain class bound to » light chains; and
(ii) immunoglobulins having the same heavy chain class but bound to º light chains; the method comprising detecting said immunoglobulins by an immunosorbant assay comprising:
(i) binding said immunoglobulins to a binding antibody specific for the immunoglobulin immobilised on a substrate or bound to a bead,
(ii) washing unbound immunoglobulins away and
(iii) using a labelled detecting antibody which detects immunoglobulin remaining bound to said binding antibody. |
