发明名称 HETEROARYL PYRIDONE AND AZA-PYRIDONE COMPOUNDS WITH ELECTROPHILIC FUNCTIONALITY
摘要 Heteroaryl pyridone and aza-pyridone amide compounds with electrophilic functionality of Formula I are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk, and for treating cancer and immune disorders such as inflammation mediated by Btk. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
申请公布号 EP3077384(A1) 申请公布日期 2016.10.12
申请号 EP20140808596 申请日期 2014.12.04
申请人 F.HOFFMANN-LA ROCHE AG 发明人 CRAWFORD, JAMES;WEI, BINQING;YOUNG, WENDY B.
分类号 C07D401/14;A61K31/5025;A61P35/00;A61P37/00;C07D495/04 主分类号 C07D401/14
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