PROCESSES AND INTERMEDIATES FOR PREPARING A MACROCYCLIC PROTEASE INHIBITOR OF HCV
摘要
Disclosed is a process for the preparation of certain intermediates, e.g. those in the scheme below: which intermediates and processes are useful in the preparation of the macrocyclic HVC inhibitor Simeprevir.
申请公布号
WO2016157058(A1)
申请公布日期
2016.10.06
申请号
WO2016IB51720
申请日期
2016.03.25
申请人
JANSSEN PHARMACEUTICALS, INC.
发明人
DEPRÉ, Dominique Paul Michel;ORMEROD, Dominic John;HORVATH, Andras;MOODY, Thomas Shaw;BROSSAT, Maude;RIANT, Olivier;VRIAMONT, Nicolas;LEMAIRE, Sébastien François Emmanuel;HERMANT, Sébastien Nicolas J