| 摘要 |
Second harmonic generation (SHG) is a nonlinear optical process which may be configured as a surface-selective detection technique that enables detection of binding interactions and conformational change in proteins and other biological targets using second harmonic-active labels attached to the target molecules. Methods, devices, and systems are disclosed for determining protein structure and dynamics using second harmonic generation (SHG) and related surface-selective nonlinear optical techniques. |
