发明名称 METHOD FOR PREDICTING INTERFERON THERAPEUTIC EFFICACY, AND DRUG COMPOSITION FOR HEPATITIS B PATIENTS IN WHICH SAME IS USED
摘要 The purpose of the present invention is to provide a method for predicting patients for whom there will be a high likelihood of efficacy of sequential therapy involving interferon therapy subsequent to therapy with nucleic acid analogues. The problem can be overcome by this method for predicting interferon therapeutic efficacy, which is characterized by comprising: (1) a step for measuring IFN-λ3 concentration and HBs antigen concentration in an analyte derived from an HBV-infected patient; and (2) a step for comparing the measured IFN-λ3 concentration and HBs antigen concentration to respectively predetermined cutoff values, and, in the event that the IFN-λ3 concentration is no less than, or is greater than, the cutoff value, and the HBs antigen concentration is no greater than, or is less than, the cutoff value, predicting that interferon therapy is highly likely to be effective.
申请公布号 WO2016159178(A1) 申请公布日期 2016.10.06
申请号 WO2016JP60553 申请日期 2016.03.30
申请人 MIZOKAMI Masashi 发明人 MIZOKAMI Masashi;MURATA Kazumoto;SUGIYAMA Masaya
分类号 G01N33/68;A61K38/21;A61P31/20;G01N33/53;G01N33/576 主分类号 G01N33/68
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