| 发明名称 |
High Fidelity Restriction Endonucleases |
| 摘要 |
Methods and compositions are provided for engineering mutant enzymes with reduced star activity where the mutant enzymes have a fidelity index (FI) in a specified buffer that is greater than the FI of the non-mutated enzyme in the same buffer. |
| 申请公布号 |
US2016289660(A1) |
申请公布日期 |
2016.10.06 |
| 申请号 |
US201615133093 |
申请日期 |
2016.04.19 |
| 申请人 |
New England Biolabs, Inc. |
发明人 |
Zhu Zhenyu;Quimby Aine;Guan Shengxi;Sun Dapeng;Huang Yishu;Lai Xuhui;Chan Siu-hong;Li Xianghui;Xu Shuang-Yong;Zhang Chunhua |
| 分类号 |
C12N9/22;C12Q1/44 |
主分类号 |
C12N9/22 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
Ipswich MA US |
