发明名称 |
SLOW-RELEASE SOLID ORAL COMPOSITIONS |
摘要 |
The present invention relates to a slow-release solid oral nutraceutical and/or pharmaceutical composition comprising: a core containing a donor of methyl groups and at least one pharmaceutically acceptable excipient, and an outer coating containing shellac and/or a pharmaceutically acceptable salt thereof, magnesium stearate, and at least one pharmaceutically acceptable excipient. The coating of said solid oral composition allows the donor of methyl groups, preferably SAMe and/or a pharmaceutically acceptable salt thereof, to cross intact the gastric barrier and release the same in a continuous and complete manner along the entire digestive tract. |
申请公布号 |
US2016287519(A1) |
申请公布日期 |
2016.10.06 |
申请号 |
US201415037149 |
申请日期 |
2014.11.06 |
申请人 |
GNOSIS SPA |
发明人 |
GIOVANNONE Daniele;MIRAGLIA Niccolò;BERNA Marco |
分类号 |
A61K9/28;A61K31/7076;A61K31/519;A61K9/20 |
主分类号 |
A61K9/28 |
代理机构 |
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代理人 |
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主权项 |
1. A slow-release solid oral nutraceutical and/or pharmaceutical composition comprising:
a) a core containing a donor of methyl groups and at least one pharmaceutically acceptable excipient, and b) an outer coating containing shellac and/or a pharmaceutically acceptable salt thereof, magnesium stearate and at least one pharmaceutically acceptable excipient. |
地址 |
Milano (MI) IT |