发明名称 SLOW-RELEASE SOLID ORAL COMPOSITIONS
摘要 The present invention relates to a slow-release solid oral nutraceutical and/or pharmaceutical composition comprising: a core containing a donor of methyl groups and at least one pharmaceutically acceptable excipient, and an outer coating containing shellac and/or a pharmaceutically acceptable salt thereof, magnesium stearate, and at least one pharmaceutically acceptable excipient. The coating of said solid oral composition allows the donor of methyl groups, preferably SAMe and/or a pharmaceutically acceptable salt thereof, to cross intact the gastric barrier and release the same in a continuous and complete manner along the entire digestive tract.
申请公布号 US2016287519(A1) 申请公布日期 2016.10.06
申请号 US201415037149 申请日期 2014.11.06
申请人 GNOSIS SPA 发明人 GIOVANNONE Daniele;MIRAGLIA Niccolò;BERNA Marco
分类号 A61K9/28;A61K31/7076;A61K31/519;A61K9/20 主分类号 A61K9/28
代理机构 代理人
主权项 1. A slow-release solid oral nutraceutical and/or pharmaceutical composition comprising: a) a core containing a donor of methyl groups and at least one pharmaceutically acceptable excipient, and b) an outer coating containing shellac and/or a pharmaceutically acceptable salt thereof, magnesium stearate and at least one pharmaceutically acceptable excipient.
地址 Milano (MI) IT