| 摘要 |
The present disclosure provides an ion-selective membrane for use in electrochemical biosensors for potentiometric measurement of clinically important electrolytes such as potassium ion, sodium ion, chloride ion, calcium ion and p H in biological fluids, wherein the ion-selective membrane can be formed from a membrane formulation which can include an ionophore selective for target ion, at least one polymeric material, at least one plasticizer, and a pore former. The present disclosure further provides an electrochemical biosensor for measuring target ion in a biological fluid, wherein the biosensor can include (a) a polymeric base plate, (b) at least one ion selective electrode and a reference electrode disposed on the polymeric base plate, (c) an ion selective membrane covering at least a portion of the ion selective electrode and the reference electrode, wherein the ion selective membrane is formed from a membrane formulation comprises an ionophore selective for the target ion, at least one polymeric material, at least one plasticizer, and a pore former. |
