METHODS AND MATERIALS FOR TREATING HEMATOLOGICAL MALIGNANCIES

摘要

This document provides methods and materials involved in treating hematological malignancies. For example, methods and materials for using telomerase inhibitors to treat hematological malignancies such as hematological malignancies with a spliceosome mutation genotype or presenting with ringed sideroblasts within bone marrow are provided.

主权项

1. A method for treating a hematological malignancy, wherein said method comprises administering imetelstat or imetelstat sodium to a mammal identified as having a hematological malignancy with the presence of a spliceosome mutation genotype, ringed sideroblasts within bone marrow, or both under conditions wherein said hematological malignancy is treated.