发明名称 |
SUBSTITUTED PYRROLIDINES AS FACTOR XIA INHIBITORS FOR THE TREATMENT THROMBOEMBOLIC DISEASES |
摘要 |
The present invention provides compounds of the general formula (I), their salts and N-oxides, and solvates and prodrugs thereof (wherein the substituents are as defined in the description). The compounds of the general formula (I) are inhibitors of factor XIa, and are useful in the prevention of and/or therapy for thromboembolic diseases.; |
申请公布号 |
US2016287582(A1) |
申请公布日期 |
2016.10.06 |
申请号 |
US201615180382 |
申请日期 |
2016.06.13 |
申请人 |
ONO PHARMACEUTICAL CO., LTD. |
发明人 |
IMAGAWA Akira;KONDO Takashi;NISHIYAMA Taihei;COURTNEY Steve;YARNOLD Chris;ICHIHARA Osamu;FLANAGAN Stuart |
分类号 |
A61K31/496 |
主分类号 |
A61K31/496 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Osaka JP |