发明名称 |
New crystalline form VI of agomelatine, method of preparation and pharmaceutical compositions thereof |
摘要 |
A crystalline form VI of agomelatine having X-ray powder diffraction diagram and infra-red spectrum as given in the specification, is new. A crystalline form VI of agomelatine of formula (L1) having X-ray powder diffraction diagram and infra-red spectrum as given in the specification, is new. An independent claim is included for preparation of the crystalline form VI of agomelatine (L1). [Image] ACTIVITY : CNS-Gen.; Hypnotic; Tranquilizer; Antidepressant; Cardiovascular-Gen.; Immunomodulator; Muscular-Gen.; Neuroleptic; Anorectic; Analgesic; Anticonvulsant; Antidiabetic; Antimigraine; Cytostatic; Antiparkinsonian; Endocrine-Gen.; Nootropic. No biological data given. MECHANISM OF ACTION : Melatoninergic system receptor agonist; 5-Hydroxytryptamine 2c receptor antagonist. No biological data given. |
申请公布号 |
EP2058296(B1) |
申请公布日期 |
2016.10.05 |
申请号 |
EP20080291042 |
申请日期 |
2008.11.07 |
申请人 |
LES LABORATOIRES SERVIER |
发明人 |
COQUEREL, GÉRARD;LINOL, JULIE;LE PAPE, LIONEL;LECOUVE, JEAN-PIERRE |
分类号 |
C07C233/18;A61K9/20 |
主分类号 |
C07C233/18 |
代理机构 |
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