发明名称 |
STRATEGIES TO PREVENT AND/OR TREAT IMMUNE RESPONSES TO SOLUBLE ALLOFACTORS |
摘要 |
The invention relates to isolated immunogenic peptides comprising a T-cell epitope derived from a soluble allofactor and a C-(X)2-[CST] or [CST]-(X)2-C motif, which is immediately adjacent or separated from the T-cell epitope by at most 7 amino acids. The application further relates to the use of these peptides in preventing or suppressing an immune response to a soluble allofactor. The invention further relates to the use of these peptides in obtaining populations of soluble allofactor-specific regulatory T cells with cytotoxic properties. |
申请公布号 |
EP3075391(A1) |
申请公布日期 |
2016.10.05 |
申请号 |
EP20160161449 |
申请日期 |
2009.02.16 |
申请人 |
LIFE SCIENCES RESEARCH PARTNERS VZW;KATHOLIEKE UNIVERSITEIT LEUVEN |
发明人 |
SAINT-REMY, JEAN-MARIE |
分类号 |
A61K39/00;A61K39/39;C07K14/755;C12N9/02 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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