发明名称 COMPOUND AND METHOD FOR SELECTIVE RADIOLABELLING OF POLYPEPTIDES BY MEANS OF SOLID-PHASE SYNTHESIS
摘要 The invention relates to a compound of the formula (I) T-Pep-BG (I) where, in formula (I), T is a solid support; Pep is a polypeptide bonded covalently to T, where the polypeptide has an amino acid sequence having 3 to 200 amino acids and BG is an uncomplexed binding group for a metal M selected from the group consisting of 99mTc,186Re,188Re, 90Y, 86Y, 177Lu, 68Ga, 67Cu, 64Cu, 67Ga,89Zr,153Sm and 111 In. The invention further relates to a method for preparing the compound of the formula (I) and to uses and kits of the compounds of the formula (I) for production of radiodiagnostic and radiotherapeutic products.
申请公布号 EP3074407(A1) 申请公布日期 2016.10.05
申请号 EP20140809780 申请日期 2014.11.26
申请人 FREIE UNIVERSITÄT BERLIN 发明人 BARANDOV, ALI;KOKSCH, BEATE;ABRAM, ULRICH;ARAGHI, RAHELEH REZAEI
分类号 C07F9/50;A61K51/08;C07B59/00;C07F13/00 主分类号 C07F9/50
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