发明名称 APPLICATION OF LAMININ TO CORNEAL ENDOTHELIAL CELL CULTURE
摘要 The present invention provides a method of culturing corneal endothelial cells. More specifically, the present invention provides a composition for culturing or growing corneal endothelial cells, comprising at least one agent consisting of laminins and fragments thereof which express in corneal endothelial cells. Specifically, the present invention can comprise laminin 511 (alpha5 beta1 gamma1) and laminin 512 (alpha5 beta2 gamma 1). The present invention further provides a culture container for corneal endothelial cells, which is coated with the composition of the present invention. Furthermore, the present invention provides a method for culturing corneal endothelial cells comprising the step of using the composition or the container of the present invention to culture the corneal endothelial cells.
申请公布号 EP3074508(A1) 申请公布日期 2016.10.05
申请号 EP20140831100 申请日期 2014.11.26
申请人 KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION;THE DOSHISHA;SENJU PHARMACEUTICAL CO., LTD. 发明人 KOIZUMI, NORIKO;OKUMURA, NAOKI;KINOSHITA, SHIGERU;KRUSE, FRIEDRICH E.;SCHLOETZER-SCHREHARDT, URSULA
分类号 C12N5/079 主分类号 C12N5/079
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