COMBINATIONS OF A PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUND AND A CDK4/6 INHIBITOR COMPOUND FOR THE TREATMENT OF CANCER

摘要

Methods and compositions are provided for treating cancer in patients with a therapeutic combination comprising a therapeutically effective amounts of taselisib and palbociclib, or stereoisomers, geometric isomers, tautomers, or pharmaceutically acceptable salts thereof.

主权项

1. A method for the treatment of cancer comprising administering a therapeutic combination as a combined formulation or by alternation to a patient, wherein the therapeutic combination comprises a therapeutically effective amount of taselisib, and a therapeutically effective amount of palbociclib;
where taselisib and palbociclib have the structures: or stereoisomers, geometric isomers, tautomers, or pharmaceutically acceptable salts thereof.