发明名称 |
COMPOSITION COMPRISING VEMURAFENIB AND HPMC-AS |
摘要 |
The present invention relates to a premix comprising vemurafenib, in particular vemurafenib hydrochloride, and hydroxypropyl methyl cellulose acetate succinate, which is herein referred to as HPMC-AS in a specific weight ratio and to oral dosage forms comprising said premix. Further, the invention relates to a process for producing said premix comprising vemurafenib hydrochloride and HPMC-AS and to the corresponding process of producing an oral dosage form containing the premix of the invention. |
申请公布号 |
WO2016151065(A1) |
申请公布日期 |
2016.09.29 |
申请号 |
WO2016EP56485 |
申请日期 |
2016.03.24 |
申请人 |
RATIOPHARM GMBH |
发明人 |
LEHMANN, Frank;GUSERLE, Richard;ALBRECHT, Wolfgang |
分类号 |
A61K47/38;A61K9/16;A61K9/50;A61K31/437;A61K47/48 |
主分类号 |
A61K47/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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