发明名称 |
COVALENTLY LINKED HELICAR-ANTI-HELICAR ANTIBODY CONJUGATES AND USES THEREOF. |
摘要 |
Herein is reported a conjugate comprising a helicar motif amino acid sequence containing compound and an antibody that specifically binds to the helicar motif amino acid sequence characterized by a covalent bond between the helicar motif amino acid sequence containing compound and an amino acid residue in the CDR2 of the anti-helicar antibody, whereby the CDR2 is determined according to Kabat. |
申请公布号 |
MX2016008189(A) |
申请公布日期 |
2016.09.29 |
申请号 |
MX20160008189 |
申请日期 |
2014.12.29 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
Guy GEORGES;Ekkehard MOESSNER;Georg TIEFENTHALER;Ulrich BRINKMANN;Eike HOFFMANN;Stefan DENGL;Achim GAERTNER |
分类号 |
A61K47/48;C07K16/44;C07K16/46 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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