发明名称 |
CHIMERIC ANTIGEN RECEPTOR |
摘要 |
The present invention provides a chimeric antigen-receptor (CAR)-forming polypeptide comprising: (i) an antigen-binding domain; (ii) a coiled-coil spacer domain; (iii) a transmembrane domain; and (iv) an endodomain. The invention also provides a multimeric CAR formed by association of a plurality of CAR- forming polypeptides by virtue of association of their coiled-coil spacer domains. |
申请公布号 |
WO2016151315(A1) |
申请公布日期 |
2016.09.29 |
申请号 |
WO2016GB50795 |
申请日期 |
2016.03.22 |
申请人 |
UCL BUSINESS PLC |
发明人 |
PULÉ, Martin;CORDOBA, Shaun |
分类号 |
C07K14/705;A61K35/17 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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