发明名称 |
New co-crystals of agomelatin. |
摘要 |
Agomelatine cocrystals comprising agomelatine or N-[2-(7-methoxy-1-naphthyl)ethyl]acetamide and an organic acid having a solid state at room temperature, are new. An independent claim is included for the preparation of cocrystals. ACTIVITY : Tranquilizer; Hypnotic; Neuroprotective; Antidepressant; Cardiovascular-Gen.; Gastrointestinal-Gen.; CNS-Gen.; Muscular-Gen.; Neuroleptic; Anorectic; Analgesic; Anticonvulsant; Antidiabetic; Antiparkinsonian; Nootropic; Dermatological; Antimigraine; Endocrine-Gen.; Contraceptive; Immunomodulator; Cytostatic. MECHANISM OF ACTION : Melatoninergic system receptor agonist; Hydroxytryptamine receptor antagonist. |
申请公布号 |
EP2532647(B1) |
申请公布日期 |
2016.09.28 |
申请号 |
EP20120171231 |
申请日期 |
2012.06.08 |
申请人 |
LES LABORATOIRES SERVIER |
发明人 |
LETELLIER, PHILIPPE;LYNCH, MICHAEL;PEAN, JEAN-MANUEL |
分类号 |
C07C231/12;A61K31/165;A61P3/00;A61P25/16;A61P25/18;A61P25/28;C07C233/18 |
主分类号 |
C07C231/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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