发明名称 ヘテロ二量化ポリペプチド
摘要 The present inventors produced a heterodimerized polypeptide having an Fc region formed from two polypeptides with different amino acid sequences (a first polypeptide and a second polypeptide), and succeeded in producing a heterodimerized polypeptide containing an Fc region with improved Fc region function compared to that of a homodimer in which the Fc region is composed of only the first polypeptide or only the second polypeptide by conventional technology.
申请公布号 JP5997151(B2) 申请公布日期 2016.09.28
申请号 JP20130522970 申请日期 2012.06.29
申请人 中外製薬株式会社 发明人 味元 風太;倉持 太一;井川 智之;川添 明里;堅田 仁;白岩 宙丈;門野 正次郎
分类号 C12N15/09;A61K39/395;C07K16/28;C12P21/08 主分类号 C12N15/09
代理机构 代理人
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