发明名称 免疫細胞含有組成物の製造方法及び癌治療用組成物
摘要 To provide a method in which mononuclear cells are differentiated into a good balance of NK cells, NKT cells, and T cells, and said cells are made to proliferate. The present invention provides a method for manufacturing an immune cell-containing composition, said method including the following steps: a first step in which mononuclear cells are cultured in a medium containing anti-CD16 monoclonal antibodies and either IL-2 and/or IL-15; and a second step, after the first step, in which culturing is performed under conditions that make the mononuclear cells preferentially differentiate into cytotoxic T cells. This method may also include a third step, after the second step, in which culturing is performed in a medium containing anti-CD16 monoclonal antibodies and either IL-2 and/or IL-15.
申请公布号 JP5997296(B2) 申请公布日期 2016.09.28
申请号 JP20140557465 申请日期 2014.01.14
申请人 阿部 博幸;遊佐 精一 发明人 阿部 博幸;遊佐 精一
分类号 C12N5/0783;A61K35/17;A61P35/00;C12N5/078 主分类号 C12N5/0783
代理机构 代理人
主权项
地址