摘要 |
The present invention concerns culture medium for specifically selecting gram-negative, aerobe bacteria that have an acquired resistance to polymyxins as well as bacteria that are naturally resistant to polymyxins. In particular, the culture medium allows selection of Enterobacteriaceae, Pseudomonas aeruginosa and Acinetobacter baumannii having an acquired resistance to polymyxins. Presently existing culture media select naturally resistant bacteria, but were found not to select bacteria that have an acquired resistance to polymyxins. The use of polymyxin antibiotics in humans has increased recently, as a last resort treatment against infections by multidrug resistant (MDR) bacteria. The present invention identifies and resolves the need for a diagnostic test for the identification and characterization of bacteria that have an acquired resistance to polymyxins as well. |