| 摘要 |
It is intended to provide a therapeutic agent and/or a preventive agent for pain or a therapeutic agent and/or a preventive agent for a sodium channel associated disease. The present invention provides a compound represented by the following formula (I) or a pharmacologically acceptable salt thereof:
Ar 1 and Ar 2 : a heteroaryl group or an aryl group; R 1 , R 2 and R 3 : a hydrogen atom, a halogen atom, a C1-C6 alkyl group, a halogenated C1-C6 alkyl group, a hydroxy C1-C6 alkyl group, a C1-C6 alkoxy C1-C6 alkyl group or a C3-C7 cycloalkyl group or a cyano group; R 4 and R 5 : a hydrogen atom, a halogen atom, a C1-C6 alkyl group, a halogenated C1-C6 alkyl group, a hydroxyl group, a hydroxy C1-C6 alkyl group, a C1-C6 alkoxy C1-C6 alkyl group, a C3-C7 cycloalkyl group or a C1-C6 alkoxy group;
n: an integer of 1 to 3; and
the heteroaryl group or the aryl group optionally has one or two groups independently selected from a halogen atom, a C1-C6 alkyl group, a halogenated C1-C6 alkyl group, a hydroxyl group, a hydroxy C1-C6 alkyl group, a C1-C6 alkoxy C1-C6 alkyl group, a C3-C7 cycloalkyl group, a carboxyl group, a cyano group, an amino group, a C1-C3 alkylamino group and a di-Cl-C3 alkylamino group, and when the heteroaryl group or the aryl group has two such groups, the two groups are the same as or different from each other. |
