HUMANIZED ANTIBODIES THAT SEQUESTER AMYLOID BETA PEPTIDE
摘要
A method to treat conditions characterized by formation of amyloid plaques both prophylactically and therapeutically is described. The method employs humanized antibodies which sequester soluble Aß peptide from human biological fluids or which preferably specifically bind an epitope contained within position 13-28 of the amyloid beta peptide Aß.
申请公布号
EP3070100(A1)
申请公布日期
2016.09.21
申请号
EP20160161726
申请日期
2001.02.26
申请人
WASHINGTON UNIVERSITY ST. LOUIS;ELI LILLY & COMPANY
发明人
HOLTZMAN, DAVID M.;DEMATTOS, RONALD;BALES, KELLY R;PAUL, STEVEN M.;TSURUSHITA, NAOYA;VASQUEZ, MAXIMILIANO