发明名称 |
SALTS AND POLYMORPHS OF 8-FLUORO-2-{4-[(METHYLAMINO}METHYL]PHENYL}-1,3,4,5-TETRAHYDRO-6H-AZEPINO[5,4,3-CD]INDOL-6-ONE |
摘要 |
The present invention relates to novel polymorphic forms of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity including the disease condition such as cancer. |
申请公布号 |
EP2534153(B1) |
申请公布日期 |
2016.09.21 |
申请号 |
EP20110708094 |
申请日期 |
2011.02.10 |
申请人 |
PFIZER INC. |
发明人 |
BASFORD, PATRICIA, ANN;CAMPETA, ANTHONY, MICHAEL;GILLMORE, ADAM;JONES, MATTHEW, CAMERON;KOUGOULOS, ELEFTHERIOS;LUTHRA, SUMAN;WALTON, ROBERT |
分类号 |
A61K45/06;A61K31/55;C07C57/145;C07C309/19;C07D487/06 |
主分类号 |
A61K45/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|