发明名称 |
Methods for inhibiting the binding of endosialin to ligands |
摘要 |
The invention provides methods for inhibiting the interaction of endosialin with endosialin ligands. The inhibition is effectuated by blocking the interaction of cell-surface expressed endosialin with ligands such as fibronectin and collagen with the anti-endosialin antibody M4, also known as FB5. |
申请公布号 |
EP2620451(B1) |
申请公布日期 |
2016.09.14 |
申请号 |
EP20130162773 |
申请日期 |
2008.04.04 |
申请人 |
MORPHOTEK, INC. |
发明人 |
ZHOU, YUHONG;TOMKOWICZ, BRIAN E.;GRASSO, LUIGI;SASS, PHILIP M.;NICOLAIDES, NICOLAS C. |
分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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