发明名称 |
ENHANCED AAV-MEDIATED GENE TRANSFER FOR RETINAL THERAPIES |
摘要 |
Described herein are capsid proteins and adeno-associated viruses capable of targeting various types of ocular cells including bipolar and horizontal cells. Also described herein are methods of treating various ocular disorders in a subject in need thereof by administering to the subject an effective concentration of a composition comprising the recombinant adeno-associated virus (AAV) of the invention. |
申请公布号 |
EP2954051(A4) |
申请公布日期 |
2016.09.14 |
申请号 |
EP20140749120 |
申请日期 |
2014.02.07 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
CRONIN, THERESE;BENNETT, JEAN;VANDENBERGHE, LUK, E. |
分类号 |
C12N7/01;A61P27/02;C07K14/015;C12N15/864 |
主分类号 |
C12N7/01 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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