发明名称 |
METHODS FOR INHIBITING TIE2 KINASE USEFUL IN THE TREATMENT OF CANCER |
摘要 |
The present invention relates to methods of inhibiting TIE2 kinase useful in the treatment of tumor growth, invasiveness, intravasation, dissemination, metastasis, and immunosuppression. Specifically, the invention relates to methods of using 1-(3-tert-butyl-1-(quinolin-6-yl)-1Hpyrazol- 5-yl)-3-(2-fluoro-4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea and salts thereof of Formula I. |
申请公布号 |
EP3065549(A1) |
申请公布日期 |
2016.09.14 |
申请号 |
EP20130896951 |
申请日期 |
2013.11.07 |
申请人 |
DECIPHERA PHARMACEUTICALS, LLC |
发明人 |
FLYNN, DANIEL L.;KAUFMAN, MICHAEL D.;SMITH, BRYAN;RUDOLTZ, MARC S. |
分类号 |
A01N43/56;A01N47/28;C07D231/00 |
主分类号 |
A01N43/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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