| 摘要 |
In recent years, antibody drugs have garnered interest as a cancer treatment, but while in some cases the activity of the antibodies was too weak to achieve sufficient treatment results, in other cases, high dosage amounts led to too high a cost burden on patients. For that reason, increasing immune activity has become an important issue for antibody therapy drugs, and there is need for an antibody treatment adjuvant capable of enhancing the effect of antibody drugs and thereby suppressing the amount thereof used. If lymphocytes can be made to migrate and collect in and around a tumor, the effectiveness of an antibody drug may be further improved. The purpose of the present invention is to provide a safe and low-cost antibody treatment adjuvant therapy drug capable of enhancing the effect of antibody drugs. Implantation of a dense body of ß-tricalcium phosphate (TCP) into the body functions to allow activity, migration and accumulation of immune cells. The inventors discovered that the therapeutic effect of antibody drugs can be enhanced by utilizing this function, which led to the perfection of the present invention. |
