CELL SORTING METHOD

摘要

Provided is a pluripotent stem cell-derived differentiated cell with a reduced tumor risk. A method of removing or reducing undifferentiated cells from a differentiated cell population contaminated or having a risk of contamination with undifferentiated cells, including contacting a pigment epithelium-derived factor with the differentiated cell population to induce apoptosis of the undifferentiated cells. An agent for cell transplantation therapy, containing a differentiated cell population substantially free of an undifferentiated cell, which is obtained by the method. An agent for inducing apoptosis of an undifferentiated cell, containing a pigment epithelium-derived factor. Combined use of the aforementioned agent for cell transplantation therapy and the aforementioned agent for inducing apoptosis.