发明名称 |
IN VITRO POINT-OF-CARE SENSOR AND METHOD OF USE |
摘要 |
An in vitro sensor for point-of-care detection of at least one analyte or reaction product includes an inert, impermeable substrate, a sensing system, and a reference system. The substrate includes a first transparent surface oppositely disposed from a second surface and first and second cavities. Each of the first and second cavities defines an opening at the second surface. The sensing system is disposed in at least a portion of the first cavity and includes an analyte-detection optode membrane, an analyte-permeable membrane, and a plurality of non-transparent microbeads associated with at least one of the analyte-detection optode membrane and the analyte-permeable membrane. The analyte-permeable membrane is layered upon the analyte-detection optode membrane and covers the opening of the first cavity. The reference system is disposed in at least a portion of the second cavity. |
申请公布号 |
EP2591355(B1) |
申请公布日期 |
2016.09.07 |
申请号 |
EP20110816753 |
申请日期 |
2011.07.11 |
申请人 |
CASE WESTERN RESERVE UNIVERSITY |
发明人 |
PESHKOVA, MARIA;KRIKORIAN, ARMAND;NAIR, SUMITHA;AHUJA, PUNKAJ;GRATZL, MIKLOS |
分类号 |
G01N33/48;G01N21/77;G01N21/78;G01N21/80;G01N33/483;G01N33/52;G01N33/543;G01N35/00 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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