The present invention relates to methods for transferring a nucleic acid in vivo into skin cells wherein the nucleic acid is injected by intradermal (ID) injection and is electrically transferred into skin cells with a single pulse of a High Voltage, followed, after a defined lag time, by a single pulse of Low Voltage.
申请公布号
EP3063280(A1)
申请公布日期
2016.09.07
申请号
EP20140790591
申请日期
2014.10.28
申请人
INVECTYS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
发明人
LANGLADE DEMOYEN, PIERRE;HUET, THIERRY;LIARD, CHRISTELLE;THALMENSI, JESSIE;MIR, LUIS M.;CALVET, CHRISTOPHE