| 发明名称 |
METHODS AND COMPOSITIONS FOR TREATMENT OF ANGELMAN SYNDROME |
| 摘要 |
Methods for the treatment of Angelman Syndrome autism spectrum disorders are provided. The methods comprise administrating to a subject an agent that increases the expression of or increases activity of, ?-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) at neuronal synapses. |
| 申请公布号 |
EP2544688(B1) |
申请公布日期 |
2016.09.07 |
| 申请号 |
EP20110751202 |
申请日期 |
2011.03.01 |
| 申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;CHILDREN'S MEDICAL CENTER CORPORATION |
发明人 |
GREENBERG, MICHAEL, E.;GREER, PAUL, L. |
| 分类号 |
A61K31/47;A61K31/44;A61K31/4436;A61K31/4525;A61K31/4725;A61K31/54;A61K31/635;A61K31/7105;A61K38/16;A61K38/17;A61K39/395;A61K48/00;A61P25/00 |
主分类号 |
A61K31/47 |
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