| 发明名称 |
AMINE LINKED MODULATORS OF Y-SECRETASE |
| 摘要 |
The present invention relates to compounds of Formula I as shown below, wherein the definitions of A, X, Y, R1 R2, R3, R4, R5, R6, R7, R8, and R9 are provided in the specification. Compounds of Formula I are useful for the treatment of diseases associated with γ-secretase activity, including Alzheimer's disease. |
| 申请公布号 |
EP2212277(B1) |
申请公布日期 |
2016.08.31 |
| 申请号 |
EP20080839840 |
申请日期 |
2008.10.17 |
| 申请人 |
JANSSEN PHARMACEUTICA, N.V.;CELLZOME LIMITED |
发明人 |
HO, CHIH YUNG;ZHANG, YAN;MAHAROOF, UMAR S. M.;HARRISON, JOHN;MAJOR, JEREMY;BURCKHARDT, SVENJA;JONES, ALISON |
| 分类号 |
C07C229/34;A61K31/195;A61K31/404;A61K31/435;A61P25/28;C07C229/42;C07C255/58;C07D209/08;C07D213/74;C07D215/06;C07D215/38;C07D217/04 |
主分类号 |
C07C229/34 |
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