发明名称 Use of an egfr targeted antibody and a tyrosine kinase inhibitor combination for the preparation of a medicament for treatment of cancer
摘要 The present invention relates to a method of treating patients suffering from cancers driven by deregulated Human Epidermal Growth Factor Receptor (HER/Human EGFR), wherein an irreversible tyrosine kinase inhibitor (TKI) is administered according to a continuous regimen based on an average daily dose in the range of 10 to 50 mg and the mAB is co-administered according to a dosing regimen ranging from an average weekly iv dose of 50 to 500 mg/m2 repeated thrice, twice or once a week, once in two weeks, once in three weeks or at least monthly to a patient in need of such treatment.
申请公布号 IL228741(A) 申请公布日期 2016.08.31
申请号 IL20130228741 申请日期 2013.10.06
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人
分类号 A61K;A61P 主分类号 A61K
代理机构 代理人
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