摘要 |
An object of the present invention is to provide a VEGFR2 inhibitor peptide having high specificity and available at a low cost. The present invention provides a peptide having the following amino acid sequence:
[wherein, Xaa 2 represents Val or derivative thereof, Xaa 6 represents Asp or derivative thereof, Xaa 7 represents Pro or derivative thereof, Xaa 8 represents Trp or derivative thereof, Xaa 10 represents Asn or derivative thereof, Xaa 11 represents Gly or derivative thereof, Xaa 12 represents Leu or derivative thereof, Xaa 1 , Xaa 3 to Xaa 5 , Xaa 9 , and Xaa 13 to Xaa 15 each independently represent an arbitrary amino acid or derivative thereof]; or
[wherein, Xaa 24 represents His or derivative thereof, Xaa 25 represents Pro or derivative thereof, and Xaa 16 to Xaa 23 and Xaa 26 to Xaa 30 each represent an arbitrary amino acid]. |
申请人 |
THE UNIVERSITY OF TOKYO;PEPTIDREAM INC. |
发明人 |
MURAKAMI, HIROSHI;KAWAKAMI, TAKASHI;ISHIZAWA, TAKAHIRO;SUGA, HIROAKI;REID, PATRICK |