发明名称 |
METHODS AND COMPOSITIONS FOR DIAGNOSIS AND TREATMENT OF DISORDERS IN PATIENTS WITH ELEVATED LEVELS OF TLR4 LIGANDS AND OTHER BIOMARKERS |
摘要 |
This invention relates generally to methods and compositions for diagnosing and treating disorders associated with elevated levels of Toll-like Receptor 4 (TLR4) ligands and other biomarkers. The invention also relates to methods of treating, delaying the progression of, or otherwise ameliorating a symptom of a disorder associated with elevated levels of TLR4 ligands and other biomarkers using agents that interfere with or otherwise antagonize TLR4 signaling, including neutralizing anti-TLR4 antibodies. |
申请公布号 |
EP3060250(A1) |
申请公布日期 |
2016.08.31 |
申请号 |
EP20140793805 |
申请日期 |
2014.10.22 |
申请人 |
NOVIMMUNE SA |
发明人 |
DE MIN, CRISTINA;SHANG, LIMIN;MONNET, EMMANUEL;ELSON, GREG;HATTERER, ERIC |
分类号 |
A61K39/395;C07K16/28 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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