发明名称 |
QUINOLINE DERIVATIVES AS PI3K KINASE INHIBITORS |
摘要 |
A series of amino-substituted fused pyridine and pyrazine derivatives, in particular amino-substituted quinoline and quinoxaline derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions. |
申请公布号 |
EP2396315(B1) |
申请公布日期 |
2016.08.31 |
申请号 |
EP20100703498 |
申请日期 |
2010.02.11 |
申请人 |
UCB BIOPHARMA SPRL |
发明人 |
ALLEN, DANIEL, REES;BROWN, JULIEN, ALISTAIR;BÜRLI, ROLAND;HAUGHAN, ALAN, FINDLAY;MACDONALD, JONATHAN, DAVID;MATTEUCCI, MIZIO;OWENS, ANDREW, PATE;RAPHY, GILLES;SAVILLE-STONES, ELIZABETH, ANNE;SHARPE, ANDREW |
分类号 |
C07D401/12;A61K31/4709;A61K31/52;A61P29/00;A61P37/00;C07D401/14;C07D471/04;C07D487/04;C07D495/04 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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