发明名称 METHOD FOR MAKING ANTIBODY FC-HETERODIMERIC MOLECULES USING ELECTROSTATIC STEERING EFFECTS
摘要 The invention relates to methods of making Fc-heterodimeric proteins or polypeptides. The invention also relates to the Fc-heterodimeric proteins or polypeptides themselves, including the individual polypeptide components that comprise the heterodimer. Nucleic acids encoding such polypeptides, expression vectors, and host cells. Moreover, the invention relates to pharmaceutical compositions comprising one of more Fc-heterodimeric proteins or polypeptides.
申请公布号 EP3061770(A1) 申请公布日期 2016.08.31
申请号 EP20150187984 申请日期 2009.01.06
申请人 AMGEN, INC 发明人 KANNAN, GUNASEKARAN;WITTEKIND, MICHAEL
分类号 C07K16/46 主分类号 C07K16/46
代理机构 代理人
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