| 摘要 |
The present invention comprises compounds of Formula (I). wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1. |
| 申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
LEONARD, KRISTI A.;BARBAY, KENT;EDWARDS, JAMES P.;KREUTTER, KEVIN D.;KUMMER, DAVID A.;MAHAROOF, UMAR;NISHIMURA, RACHEL;URBANSKI, MAUD;VENKATESAN, HARIHARAN;WANG, AIHUA;WOLIN, RONALD L.;WOODS, CRAIG R.;FOURIE, ANNE;XUE, XIAOHUA;CUMMINGS, MAXWELL D.;JONES, WILLIAM MOORE;GOLDBERG, STEVEN |
