KINASE INHIBITORS AND THEIR USE IN TREATING CANCER
摘要
The present invention is directed to novel synthetic methods for preparing a spiro cyclopropyl indolinone compound represented by Structural Formula (A): or its pharmaceutically acceptable salt thereof. Also included are synthetic intermediates described herein.
申请公布号
EP2556071(B1)
申请公布日期
2016.08.17
申请号
EP20110764988
申请日期
2011.04.06
申请人
UNIVERSITY HEALTH NETWORK
发明人
SAMPSON, PETER BRENT;LIU, YONG;LI, SZE-WAN;FORREST, BRYAN T.;PAULS, HEINZ W.;EDWARDS, LOUISE G.;FEHER, MIKLOS;PATEL, NARENDRA KUMAR B.;LAUFER, RADOSLAW;PAN, GUOHUA
